Authors: Stern CAJ, da Silva TR, Raymundi AM, de Souza CP, Hiroaki-Sato VA, Kato L, Guimarães FS, Andreatini R, Takahashi RN, Bertoglio LJ; University of Parana, University of São Paulo, Federal University of Santa Catarina

Fear is something everyone can relate to. In fact, over 25 million people in the U.S. will experience PTSD at some point in their lives. This study looked at how CBD might weaken fear-response related to an adverse memory (like PTSD).

The results of this study, while based on fear in a more esoteric sense, do appear to suggest that CBD may one day play a vital role in the management of such a prevalent disorder.

The furry subjects, 277 Wistar rats, were given a dose of CBD immediately after receiving a small electric shock. The CBD-treated subjects were found to spend less time frozen in fear when reintroduced to the context of the fearful event. This means the CBD disrupted consolidation (or more simply put: memory strengthening) of their specific and long-term fear memory.

CBD was also found to disrupt the consolidation of generalized fear memories when administered immediately after the acquisition of such fear memory. Interestingly, the timing of the administration of CBD was vital as the results demonstrated that delayed administration of the CBD dose did not have the same effective result that immediate administration did.

The findings of this study could have a huge impact on PTSD management.